Stigmasterol is a plant sterol which has been focused on the cholesterol-lowering activity and is valued as an anti-stiffness factor in the therapy of rheumatic diseases.

Preincubation of Stigmasterol to IL-1beta-treated cells shows significant reduction of MMP-3 mRNA in human and mouse, MMP-3 protein in mouse, MMP-13 mRNA in mouse and human, ADAMTS-4 mRNA in human, PGE2 protein in human and mouse. Stigmasterol is also capable of counteracting the IL-1beta-induced NF-κB pathway^[1].

412.69

Solid

C₂₉H₄₈O

83-48-7

豆甾醇

• Steroids

• Plants
• Amaranthaceae
• Achyranthes bidentata

Room temperature in continental US; may vary elsewhere.

Acetone : 6.67 mg/mL(16.16 mM;Need ultrasonic)

DMF : 1 mg/mL(2.42 mM;ultrasonic and warming and heat to 60℃)

H₂O :< 0.1 mg/mL(insoluble)

1M NaOH :< 1 mg/mL(insoluble)

Ethanol :< 1 mg/mL(insoluble)

DMSO :< 1 mg/mL(insoluble or slightly soluble)

MEOH :< 1 mg/mL(insoluble)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。