Lomitapide mesylate(AEGR-733; BMS-201038) is an inhibitor of microsomal triglyceride-transfer protein (MTP) wtih in vitro IC50 of 8 nM. IC50 value: 8 nM [1] Target: MTP inhibitor Lomitapide is a small-molecule,microsomal triglyceride transfer protein (MTP)inhibitor, for the treatment of both familial and primary hypercholesterolemia. Oral, once-daily lomitapide will be targeted at patients resistant toHMG-CoA reductaseinhibitors (statins) either due to abnormalities in liver function or to discontinuation because of muscle pain.

789.83

C₄₀H₄₁F₆N₃O₅S

202914-84-9

甲磺酸洛美他派

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.