| CAS NO: | 137338-43-3 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 20mg | 电议 |
| Cas No. | 137338-43-3 |
| Canonical SMILES | CS(=O)(NC1=CN(C)C2=C(C=CC=C2)C1=O)=O |
| 分子式 | C11H12N2O3S |
| 分子量 | 252.29 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | LAS-31180 is an inhibitor of phosphodiesterase 3, with positive inotropic and vasodilator properties. LAS 31180 shows positive inotropic activities in isolated guinea-pig ventricular strips (EC50 of 1.2 mumol/L) and in isolated guinea-pig working hearts[1]. In conscious chronically instrumented beagle dogs, LAS 31180 administered either by intravenous or oral route, shows a dose-dependent, long-lasting positive inotropic effect with minimal effects on heart rate. In hypertensive beagle dogs LAS 31180 elicits a potent and long-lasting fall in blood pressure[1]. [1]. Gras J, et al. Pharmacological profile of LAS 31180, a new inotropic/vasodilator quinolone derivative. Arzneimittelforschung. 2000 Nov;50(11):980-6. |
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