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IDO-IN-3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
IDO-IN-3图片
CAS NO:2070018-30-1
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
2mg电议
5mg电议
10mg电议
50mg电议

产品介绍
IDO-IN-3是一种有效的吲哚胺-2,3-双加氧酶(IDO)抑制剂,IC50为290nM。
Cas No.2070018-30-1
Canonical SMILESO/N=C(NC1=CC(Br)=C(F)C=C1)\C2=NON=C2NCCN
分子式C11H12BrFN6O2
分子量359.15
溶解度DMSO : 27.5 mg/mL (76.57 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 290 nM.

IDO-IN-3 (Compound 4c) is a potent (HeLa IC50=98 nM) inhibitor of IDO[1].

[1]. Yue EW, et al. INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology. ACS Med Chem Lett. 2017 Mar 6;8(5):486-491.