CAS NO: | 2070018-30-1 |
包装 | 价格(元) |
10mM (in 1mL DMSO) | 电议 |
2mg | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
Cas No. | 2070018-30-1 |
Canonical SMILES | O/N=C(NC1=CC(Br)=C(F)C=C1)\C2=NON=C2NCCN |
分子式 | C11H12BrFN6O2 |
分子量 | 359.15 |
溶解度 | DMSO : 27.5 mg/mL (76.57 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | IDO-IN-3 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 290 nM. IDO-IN-3 (Compound 4c) is a potent (HeLa IC50=98 nM) inhibitor of IDO[1]. [1]. Yue EW, et al. INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology. ACS Med Chem Lett. 2017 Mar 6;8(5):486-491. |