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Cabotegravir-d3 sodium
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cabotegravir-d3 sodium图片
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品名称
GSK-1265744-d3 sodium
S/GSK1265744-d3 sodium
产品介绍
Cabotegravir-d3 sodium 是 Cabotegravir sodium 的氘代物。 Cabotegravir sodium 一种高效的HIV整合酶抑制剂,对 HIVADAIC50为 2.5 nM。Cabotegravir sodium 主要由尿苷二磷酸葡萄糖醛酸转移酶 (UGT) 1A1 代谢,与其他抗逆转录病毒药物 (ARVs) 相互作用的可能性较低。
生物活性

Cabotegravir-d3 sodium is the deuterium labeled Cabotegravir sodium. Cabotegravir sodium is a highly potentHIV integrase inhibitorwith an IC50 value of 2.5 nM for HIVADA. Cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltr

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

430.35

Formula

C19H13D3F2N3NaO5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.