FTO-IN-8 (FTO-43) is a N6-methyladenosine demethylase (FTO) (fat mass- and obesity-associated protein) inhibitor with theIC₅₀value of 5.5 μM. FTO-IN-8 has anti-cancer cell proliferative activity^[1].

FTO-IN-8 (FTO-43) (0-50 μM, 24-72 h) inhibits the proliferation of cancer cells with no cytotoxicity to normal colonic cells^[1].
FTO-IN-8 (FTO-43) can increase m⁶A and m⁶A_mlevels and inhibits Wnt/PI3K-Akt signaling in gastric cancer AGS cells^[1].

346.85

Oil

C₁₉H₂₃ClN₂O₂

2640366-38-5

Room temperature in continental US; may vary elsewhere.

DMSO : ≥ 100 mg/mL(288.31 mM)

*"≥" means soluble, but saturation unknown.

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