CAS NO: | 20958-15-0 |
包装: | 5mg |
市场价: | 4770元 |
IsotanshinoneIIA,一个松香型二萜代谢物,能够抑制蛋白酪氨酸磷酸酶1B(PTP1B)的活性,其IC50值为11.4μM。
Cas No. | 20958-15-0 |
别名 | 异丹参酮IIA |
Canonical SMILES | O=C1C2=C(C3=C(C=C2)C(C)(C)CCC3)C(C4=C1C(C)=CO4)=O |
分子式 | C19H18O3 |
分子量 | 294.34 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Isotanshinone IIA, an abietane-type diterpene metabolite, could non-competitively inhibit Protein Tyrosine Phosphatase 1B (PTP1B) activity with an IC50 0f 11.4 μM. [1]. Han YM, et al. PTP1B inhibitory effect of abietane diterpenes isolated from Salvia miltiorrhiza. Biol Pharm Bull. 2005 Sep;28(9):1795-7. |