CAS NO: | 114870-03-0 |
包装 | 价格(元) |
10 mM * 1 mL in Water | 电议 |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
50mg | 电议 |
100mg | 电议 |
200mg | 电议 |
生物活性 | Fondaparinux sodium is an antithrombin-dependentfactor Xainhibitor. | ||||||||||||||||
IC50& Target | Factor Xa[1] | ||||||||||||||||
体外研究 (In Vitro) | Fondaparinux sodium is the first agent of a new class of anticoagulants that selectively target factor Xa. For Fondaparinux, its IC50values (anti-Xa IU/ml) are 0.59±0.05 for activated monocytes (ac-M) and 0.17±0.03 for monocyte-derived microparticles (MMPs)[2]. | ||||||||||||||||
体内研究 (In Vivo) | Fondaparinux sodium has a linear, dose-dependent pharmacokinetic profile, which provides a highly predictable response. Fondaparinux sodium is 100% bioavailable, has a rapid onset of action, and has a half-life of 14 to 16 hours, allowing for sustained antithrombotic activity over a 24-hour period. The drug does not affect prothrombin time or activated partial thromboplastin time, nor does it affect platelet function or aggregation[1]. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 1728.08 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C31H43N3Na10O49S8 | ||||||||||||||||
CAS 号 | 114870-03-0 | ||||||||||||||||
中文名称 | 磺达肝癸钠;磺达肝素钠 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: H2O : 125 mg/mL(72.33 mM;Need ultrasonic) 配制储备液
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以下溶剂前显示的百
*以上所有助溶剂都可在本网站选购。 |