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Humantenmine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Humantenmine图片
CAS NO:82354-38-9
包装与价格:
包装价格(元)
5mg电议
10mg电议

产品介绍
Humantenmine 是可从中国线虫中分离出来的一种生物碱,有用于疼痛和风湿性关节炎的潜力。
Cas No.82354-38-9
别名葫蔓藤碱甲,Gelsenicine
Canonical SMILESO=C1[C@]2([C@H](OC3)C[C@]4([H])[C@@]3([H])[C@@H](N=C4CC)C2)C5=CC=CC=C5N1OC
分子式C19H22N2O3
分子量326.39
溶解度Soluble in DMSO
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Humantenmine, a newalkaloid isolated from Gelsemium elegan Banth in China, has the potential for pain and rheumatic arthritis treatment[1][2].

[1]. Kun Yang, et al. Development and In-House Validation of a Sensitive LC-MS/MS Method for Simultaneous Quantification of Gelsemine, Koumine and Humantenmine in Porcine Plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Feb 15;1076:54-60. [2]. Rongjin Sun, et al. CYP3A4/5 Mediates the Metabolic Detoxification of Humantenmine, a Highly Toxic Alkaloid From Gelsemium Elegans Benth. J Appl Toxicol. 2019 Sep;39(9):1283-1292.