包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | VEGFR-2/DHFR-IN-2 (compound 5b) is an inhibitor ofVEGFR-2andDHFRwithIC50s of 0.623 and 9.085 μM, respectively. VEGFR-2/DHFR-IN-2 exhibits good cytotoxic activities against C26, HepG2, and MCF7cancercell lines withIC50values of 3.59-8.38 μM. VEGFR-2/DHFR-IN-2 can be used for the research ofcancer[1]. | ||||||||
IC50& Target |
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体外研究 (In Vitro) | VEGFR-2/DHFR-IN-2 (2-1024 μg/mL; 18-72 h) shows antibacterial and antifungal activities with MIC values of 64, 64, 32, 32, 16, 32, 64 and 256 μg/mL forEscherichia coli,Pseudomonas aeruginosa,Streptococcus faecalis,Salmonella enterica,MSSA,MRSA,Candida albicansandAspergillus niger, respectively[1].VEGFR-2/DHFR-IN-2 (0.5-100 μM; 48 h) exhibits anticancer activities[1].VEGFR-2/DHFR-IN-2 (0-100 μM; 30 min) shows DHFR and VEGFR-2 inhibitory activities with IC50s of 9.085 and 0.623 μM, respectively[1]. Cell Cytotoxicity Assay[1]
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分子量 | 351.40 | ||||||||
Formula | C21H21NO4 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |