| CAS NO: | 306301-68-8 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| Cas No. | 306301-68-8 |
| 分子式 | C25H18N4O2 |
| 分子量 | 406.44 |
| 溶解度 | DMSO : 100 mg/mL (246.04 mM; Need ultrasonic) |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | IC50: 1.2 μM (ST-hSK); 11 μM (hERK2)[1] SKI-I is a potent and selective inhibitor of humansphingosine kinase (SK), with anIC50of 1.2 μM forST-hSK. SKI-I also inhibitshERK2(IC50=11 μM). SKI-I inducesapoptosisin tumor cell lines[1][2]. SKI-I (Compound I; 5 μg/mL) inhibits SK activity by 99%[1]. |
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