RO-3 是一种有效的、CNS 渗透性和口服活性的 P2X3 和 P2X2/3 拮抗剂,对人同源多聚体 P2X3 和异源多聚体 P2X2/3 受体的 pIC50 分别为 5.9 和 7.0。
Cas No. | 1026582-88-6 |
化学名 | 5-(2-isopropyl-4,5-dimethoxybenzyl)pyrimidine-2,4-diamine |
Canonical SMILES | NC1=NC(N)=NC=C1CC(C(C(C)C)=C2)=CC(OC)=C2OC |
分子式 | C16H22N4O2 |
分子量 | 302.37 |
溶解度 | <30.24mg/ml in DMSO |
储存条件 | Store at RT |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |