Velagliflozin proline hydrate is the clinical form of Velagliflozin (HY-109018). Velagliflozin is an oralsodium-glucose cotransporter 2(SGLT2) inhibitor with antidiabetic activity. Velagliflozin reduces renal glucose reabsorption and stimulates glycosuria, which lowers blood sugar andinsulinconcentrations^[1].

Velagliflozin proline hydrate 是一种钠-葡萄糖共转运蛋白 2 (SGLT2) 抑制剂，具有抗糖尿病活性^[1]。

Velagliflozin proline hydrate (1 mg/kg, 口服, 单剂量) 增加胆固醇、白蛋白、β -羟基丁酸 (BHB)、非酯化脂肪酸 (NEFA) 和尿葡萄糖排泄，并降低猫的呼吸交换比率^[1]。
Velagliflozin proline hydrate (0.3 mg/kg; 口服; 每天 1 次, 共 18 天) 耐受性良好，可通过降低饮食非结构性碳水化合物 (NSC) 的高胰岛素反应来治疗小马的胰岛素失调和预防椎板炎^[2]。

528.59

C₂₈H₃₆N₂O₈

1661838-94-3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.