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Bepridil hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bepridil hydrochloride图片
CAS NO:68099-86-5
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议

产品介绍
Bepridil hydrochloride (CERM 1978) 是一种钙通道阻滞剂,具有抗心绞痛活性。
Cas No.68099-86-5
别名1-异丁氧基-2-吡咯烷基-3-(N-苄基苯胺基)丙烷盐酸盐,CERM 1978
化学名(R)-N-benzyl-N-(3-isobutoxy-2-(pyrrolidin-1-yl)propyl)aniline hydrochloride
Canonical SMILESCC(C)COC[C@@H](CN(C1=CC=CC=C1)CC2=CC=CC=C2)N3CCCC3.Cl
分子式C24H34N2O.HCl
分子量403
溶解度DMF: 20 mg/mL,DMSO: 5 mg/mL,Ethanol: 25 mg/mL,Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/mL
储存条件Desiccate at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Bepridil hydrochloride (CERM 1978) is a calcium channel blocker, with antianginal activity.

Bepridil hydrochloride is a calcium channel blocker, with antianginal activity[1].

Bepridil hydrochloride (21 mg/kg) reduces heart rate and mean arterial pressure, decreases the mean coronary vascular resistance and increases stroke volume in rats[1].

References:
[1]. Flaim SF, et al. Effects of bepridil hydrochloride on cardiocirculatory dynamics, coronary vascular resistance, and cardiac output distribution in normal, conscious rats. J Cardiovasc Pharmacol. 1988 Mar;11(3):363-72.