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Milbemycin A3 oxime
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Milbemycin A3 oxime图片
CAS NO:114177-14-9
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
An anthelmintic
Cas No.114177-14-9
别名美倍霉素肟A3
Canonical SMILESC[C@H]([C@@H](C)CC1)O[C@]21C[C@](OC([C@@]3([H])[C@@]4(O)[C@@]5([H])/C(C(C)=C3)=N/O)=O)([H])C[C@](C/C=C(C)/C[C@@H](C)/C=C/C=C4\CO5)([H])O2
分子式C31H43NO7
分子量541.7
溶解度DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Milbemycin A3 oxime is an anthelmintic, a derivative of milbemycin A3 , and a component of milbemycin oxide .1 It reduces the number of microfilariae of the heartworm D. immitis in the blood of naturally infested dogs by 85.2% when administered at a dose of 0.05 mg/kg. Formulations containing milbemycin A3 oxime, in combination with milbemycin A4 oxime, have been used in the treatment of parasitic infections in dogs.

|1. Tsukamoto, Y., Sato, K., Mio, S., et al. Synthesis of 5-keto-5-oxime derivatives of milbemycins and their activities against microfilariae. Agric. Biol. Chem. 55(10), 2615-2621 (1991).