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3,4-Dimethoxycinnamic acid(O-Methylferulic acid)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
3,4-Dimethoxycinnamic acid(O-Methylferulic acid)图片
CAS NO:2316-26-9
包装:100mg
市场价:446元

产品介绍
3,4-Dimethoxycinnamic acid (O-Methylferulic acid) (O-Methylferulic acid) 是从 Securidaca inappendiculata Hassk 中提取纯化的单体。
Cas No.2316-26-9
别名3,4-二甲氧基肉桂酸; O-Methylferulic acid
Canonical SMILESO=C(O)/C=C/C1=CC=C(OC)C(OC)=C1
分子式C11H12O4
分子量208.21
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

3,4-Dimethoxycinnamic acid (O-Methylferulic acid) is a monomer extracted and purified from Securidaca inappendiculata Hassk. 3,4-Dimethoxycinnamic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signaling pathway[1]. Anti-apoptotic effects[1].

3,4-Dimethoxycinnamic acid (Methyl ferulic acid; 25, 50 and 100 µM) attenuates the ethanol-induced apoptosis of ethanolexposed L-02 cells[1]. 3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) inhibits the expression levels of Nox4 and p22phox in L-02 cells[1]. 3,4-Dimethoxycinnamic acid (25, 50 and 100 µM) treatment attenuates ethanol-induced MAPK phosphorylation in L-02 cells[1].3,4-Dimethoxycinnamic acid decreases the expression levels of superoxide dismutase, catalase and phospholipid hydroperoxide gluthione peroxidase, and downregulates the levels of Bax/Bcl-2 and the cleaved forms of caspase-3 in a dose- and time-dependent manner[1].

[1]. Li L, et al. Methyl ferulic acid exerts anti-apoptotic effects on L-02 cells via the ROS-mediated signalingpathway. Int J Oncol. 2018 Jul;53(1):225-236.