[Asu1,6-Arg8]Vasopressin

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

40944-53-4

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

[Asu1,6-Arg8]Vasopressin 是一种加压素 (vasopressin) 激动剂，可增强培养的大鼠垂体前叶细胞中由促肾上腺皮质激素释放因子 (CRF) 诱导的环AMP积累和ACTH释放。

生物活性

[Asu1,6-Arg8]Vasopressin is anvasopressinagonist which potentiates cyclic AMP accumulation and ACTH release induced by corticotropin-releasing factor (CRF) in rat anterior pituitary cells in culture^[1]^[2].

体外研究
(In Vitro)

[Asu1,6-Arg8]Vasopressin (100 nM; 0-240 分钟) 使 CRF 对培养的大鼠垂体前叶细胞 ACTH释放和循环 AMP 积累的刺激作用增加2倍。[Asu1,6-Arg8]Vasopressin 单独对腺垂体细胞中的循环AMP积累在任何时间间隔都没有影响^[1]。

分子量

1033.14

Formula

C₄₈H₆₈N₁₄O₁₂

CAS 号

40944-53-4

Sequence Shortening

YFQN-Asu-PRG-NH2 (Lactam:Tyr1-Asu5)

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility

In Vitro:

H₂O

Peptide Solubility and Storage Guidelines:

1. Calculate the length of the peptide.

2. Calculate the overall charge of the entire peptide according to the following table:

	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3. Recommended solution:

Overall charge of peptide	Details
Negative (<0)	1. Try to dissolve the peptide in water first. 2. If water fails, add NH₄OH (<50 μL). 3. If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0)	1. Try to dissolve the peptide in water first. 2. If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3. If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1. Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2. For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.