N-癸酰基-L-高丝氨酸内酯是 N-酰基-高丝氨酸内酯家族的成员。
| Cas No. | 177315-87-6 |
| 别名 | 癸酰-高丝氨酸内酯,C10-HSL |
| 化学名 | N-[3S)-tetrahydro-2-oxo-3-furanyl]-decanamide |
| Canonical SMILES | O=C1[C@@H](NC(CCCCCCCCC)=O)CCO1 |
| 分子式 | C14H25NO3 |
| 分子量 | 255.4 |
| 溶解度 | DMF: 30 mg/ml,DMF:PBS (pH 7.2) (1:4): 0.2 mg/ml,DMSO: 20 mg/ml,Ethanol: 5 mg/ml |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. A promising field of study involves controlling bacterial infections by quenching their quorum sensing systems. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR family of proteins, is coordinated by synthesis of diffusible acylhomoserine lactone (AHL) molecules. N-decanoyl-L-Homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism.[1] The applications of this molecule include regulation of virulence and exoproteases.[2]
Reference:
[1]. Barnard, A.M.L., and Salmond, G.P.C. Quorum sensing: The complexities of chemical communication between bacteria Complexus 5(2), 87-101 (2004).
[2]. Williams, P. Quorum sensing, communication and cross-kingdom signalling in the bacterial world Microbiology 153 (Pt 12), 3923-3938 (2007). |
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