Cas No. | 18791-21-4 |
别名 | 吡啶霉素 |
Canonical SMILES | OC1=C(C(N[C@@H]([C@@H](C)OC(/C(O2)=C(C)/CC)=O)C(N[C@@H](CC3=CC=CN=C3)[C@@H](O)[C@@H](C)C2=O)=O)=O)N=CC=C1 |
分子式 | C27H32N4O8 |
分子量 | 540.6 |
溶解度 | DMF: Soluble,DMSO: Soluble,Ethanol: Soluble,Methanol: Soluble |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Pyridomycin is a structurally unusual antimycobacterial cyclodepsipeptide whose composition includes two rare moieties: 3-(3-pyridyl)-L-alanine and 2-hydroxy-3-methylpent-2-enoic acid. It inhibits NADH-dependent enoyl (Acyl-Carrier-Protein) reductase InhA, preventing mycolic acid synthesis in M. tuberculosis, including isoniazid-resistant strains (MICs = 0.31-0.63 µg/ml). |