17-苯基三去甲前列腺素F2α;甲酯是比马前列素的前药。
Cas No. | 38315-47-8 |
别名 | 比马前列素酸甲基酯 |
Canonical SMILES | O[C@@H]1[C@H](C/C=C\CCCC(OC)=O)[C@@H](/C=C/[C@@H](O)CCC2=CC=CC=C2)[C@H](O)C1 |
分子式 | C24H34O5 |
分子量 | 402.5 |
溶解度 | Acetonitrile: 3 mg/ml,DMF: 25 mg/ml,DMSO: 25 mg/ml,Ethanol: 50 mg/ml,PBS (pH 7.2): .25 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. 17-phenyl trinor PGF2α methyl ester is a lipophilic analog of 17-phenyl trinor PGF2α, a potent agonist for the FP receptor. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. Esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid. |