4-Methylumbelliferyl-α-D-Galactopyranoside (4MU-α-Gal)，α-galactosidase A (GLA) 的底物，是一种蓝色的促荧光底物。
| Cas No. | 38597-12-5 |
| 别名 | 4-甲基伞形酮-α-D-吡喃半乳糖苷; 4MU-α-Gal |
| Canonical SMILES | OC[C@@H]1[C@H](O)[C@H](O)[C@@H](O)[C@@H](OC2=CC=C(C(C)=CC(O3)=O)C3=C2)O1 |
| 分子式 | C16H18O8 |
| 分子量 | 338.3 |
| 溶解度 | DMF: 5 mg/ml,DMSO: 1 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 4-Methylumbelliferyl-α-D-galactopyranoside (4-MU-α-Gal) is a fluorogenic substrate of α-galactosidase. In addition to its use in characterizing novel α-galactosidases, 4-MU-α-Gal is used in assays to evaluate deficiency in α-galactosidase activity related to Fabry disease. Hydrolysis of 4-MU-α-Gal releases the fluorescent product 4-MU, which has an emission maximum at 445-454 nm. The excitation maximum for 4-MU is pH-dependent: 330, 370, and 385 nm at pH 4.6, 7.4, and 10.4, respectively. |
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