GR 87389 is a potentNK2receptorantagonist. GR 87389 antagonized GA 64349-induced smooth muscle strips contractions in a competitive manner in the human detrusor, prostate and prostatic urethra^[1][2].

GR 87389 是一种非肽和肽速激肽拮抗剂，对海马、膀胱和十二指肠的 K_i值分别为 4.0、5.2 和 14 nM^[1]。
GR 87389 (30-300 nM) 拮抗 GA 64349 诱导的人类逼尿肌、前列腺和前列腺尿道平滑肌条收缩^[2]。

900.07

C₄₇H₆₅N₉O₉

141663-86-7

{Boc}-AA-{D-Trp}-F-{D-Pro}-P-{Nle}-NH2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.