| CAS NO: | 515141-51-2 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| 生物活性 | GW-803430 (GW-3430) is a potent and selective melanin-concentrating hormone receptor 1 (MCH R1) antagonist with apIC50of 9.3. GW-803430 is orally active in an animal model of obesity[1]. | |||||||||
| IC50& Target | pIC50: 9.3 (MCH R1)[1] | |||||||||
| 体外研究 (In Vitro) | GW-803430 demonstrates a potent antagonist activity towards MCH induced MCHR1 receptor with an IC50value of ~13 nM[2]. | |||||||||
| 体内研究 (In Vivo) | GW-803430 (0.3, 3, and 15 mg/kg; oral administration; once daily) causes a sustained dose-dependent weight loss relative to vehicle controls[1].
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| 分子量 | 481.99 | |||||||||
| 性状 | Solid | |||||||||
| Formula | C25H24ClN3O3S | |||||||||
| CAS 号 | 515141-51-2 | |||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||
| 储存方式 |
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