Alclometasone Dipropionate (Sch 22219) 是一种类固醇化合物。
| Cas No. | 66734-13-2 |
| 别名 | 阿氯米松双丙酸酯,Sch 22219 |
| Canonical SMILES | O=C1C=C[C@@]2(C)C(C[C@@H](Cl)[C@]3([H])[C@]2([H])[C@@H](O)C[C@@]4(C)[C@@]3([H])C[C@@H](C)[C@@]4(C(COC(CC)=O)=O)OC(CC)=O)=C1 |
| 分子式 | C28H37ClO7 |
| 分子量 | 521 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS(pH 7.2) (1:1): 0.2 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Alclometasone dipropionate (ACM) is a corticosteroid. It reduces cutaneous anaphylaxis reactions induced by tuberculin or albumin in mice when administered topically (20 μl of a 0.1% solution). ACM also inhibits androgen-dependent cytochrome P450 activity and the O-depropylation activity of 7-alkoxy-coumarin O-dealkylase in a dose-dependent manner in male rats but has no effect on hepatic drug metabolism in female rats or mice of both sexes. Formulations containing ACM have been used to treat radiation and allergic contact dermatitis. |
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