| CAS NO: | 141750-63-2 |
| 包装 | 价格(元) |
| 500μg | 电议 |
| 1mg | 电议 |
| 5mg | 电议 |
| Cas No. | 141750-63-2 |
| 别名 | 匹伐他汀内酯 |
| Canonical SMILES | FC(C=C1)=CC=C1C2=C(/C=C/[C@H]3OC(C[C@H](O)C3)=O)C(C4CC4)=NC5=C2C=CC=C5 |
| 分子式 | C25H22FNO3 |
| 分子量 | 403.5 |
| 溶解度 | DMF: 30 mg/ml,DMSO: 30 mg/ml,DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml,Ethanol: 10 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Pitavastatin lactone is a major phase 2 metabolite of pitavastatin , an inhibitor of HMG-CoA reductase, that is found in plasma of rats and humans following oral administration., Pitavastatin lactone is formed when pitavastatin undergoes glucuronidation by the UDP-glucuronysyl transferases UGT1A1, UGT1A3, or UGT2B7 to form pitavastatin glucuronide, which then undergoes non-enzymatic conversion to pitavastatin lactone. It can be converted back to pitavastatin via hydrolysis. |
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