Herquline A (Herqueline A) 是一种真菌哌嗪生物碱。
| Cas No. | 71812-08-3 |
| 别名 | 梅花青霉素A,Herqueline A |
| Canonical SMILES | O=C(CCC1=C2)[C@@]2([H])[C@@]3([H])C(CC[C@@]4([H])[C@]3([H])N(C[C@@](C1)([H])N(C)C5)[C@@]5([H])C4)=O |
| 分子式 | C19H26N2O2 |
| 分子量 | 314.4 |
| 溶解度 | DMSO: soluble,Ethanol: soluble,Methanol: soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Herquline A is an alkaloid fungal metabolite originally isolated from P. herquei. It inhibits cell death induced by influenza A strain A/PR/8/34 in MDCK cells with an IC50 value of 10 μg/ml and inhibits viral replication in a plaque assay in a concentration-dependent manner. Herquline A also inhibits platelet aggregation induced by ADP and platelet-activating factor (PAF) in vitro (IC50s = 180 and 240 μM, respectively). |
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