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Harmalol hydrochloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Harmalol hydrochloride图片
CAS NO:6028-07-5
包装:5mg
市场价:1620元

产品介绍
Harmalolhydrochloride是一种β-咔啉生物碱,存在于几种药用植物中,如Peganumharmala。Harmalolhydrochloride,Harmaline的主要代谢产物,在转录和翻译后水平上显著抑制二恶英介导的CYP1A1诱导。Harmalolhydrochloride具有抗氧化和清除羟自由基的特性。
Cas No.6028-07-5
别名盐酸骆驼蓬酚
Canonical SMILESCC1=NCCC2=C1NC3=C2C=CC(O)=C3.[H]Cl
分子式C12H13ClN2O
分子量236.7
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Harmalol hydrochloride, a beta carboline alkaloid, presents in several medicinal plants such as Peganum harmala. Harmalol hydrochloride, main metabolite of Harmaline, significantly inhibits the dioxin-mediated induction of CYP1A1 at the transcriptional and posttranslational levels. Harmalol hydrochloride possesses antioxidant and hydroxyl radical-scavenging properties[1].

[1]. El Gendy MA, et al. Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms. Food Chem Toxicol. 2012;50(2):353-362.