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H-L-Photo-lysine hydrochloride
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
H-L-Photo-lysine hydrochloride图片
包装与价格：
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
H-L-Photo-lysine hydrochloride 是一种含有重氮基的赖氨酸氨基酸，也是一种光交联剂。H-L-Photo-lysine hydrochloride 可以选择性的插入到蛋白质中，并用于在体外和活细胞中交联蛋白质-蛋白质相互作用。H-L-Photo-lysine hydrochloride 用作紫外光激活的光交联探针。
Canonical SMILESN[C@@H](CCCCNC(OCCC1(C)N=N1)=O)C(O)=O.[H]Cl
分子式C11H21ClN4O4
分子量308.76
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

H-L-Photo-lysine hydrochloride is a diazirine-containing lysine amino acid and is a photo-cross-linker. H-L-Photo-lysine hydrochloride can site-selective incorporated into proteins and is used to crosslink protein-protein interactions in vitro and in living cells. H-L-Photo-lysine hydrochloride acts as a UV light-activated photo-crosslinking probe[1][2][3].

Photo-lysine, which is readily incorporated into proteins by native mammalian translation machinery, can be used to capture and identify proteins that recognize lysine post-translational modifications (PTMs), including 'readers' and 'erasers' of histone modifications[2].

[1]. Ai HW, et al. Probing protein-protein interactions with a genetically encoded photo-crosslinking amino acid. Chembiochem. 2011 Aug 16;12(12):1854-7. [2]. Chatterjee A, et al. Efficient viral delivery system for unnatural amino acid mutagenesis in mammalian cells. Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):11803-8. [3]. Yang T, et al. Photo-lysine captures proteins that bind lysine post-translational modifications. Nat Chem Biol. 2016 Feb;12(2):70-2.