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Cephradine monohydrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cephradine monohydrate图片
CAS NO:75975-70-1
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
头孢拉定一水合物
Cefradine monohydrate
产品介绍
Cephradine (Cefradine) monohydrate 是一种广谱且具有口服活性的头孢菌素。Cephradine monohydrate 对革兰氏阳性和革兰氏阴性病原体均有活性,可有效根除大多数已知对青霉素 G、青霉素 V 和氨苄青霉素具有抗性的产青霉素酶的微生物。Cephradine monohydrate 已用于泌尿生殖系统、胃肠道和呼吸道感染以及皮肤和软组织感染的研究。Cephradine monohydrate 通过直接抑制TOPK抑制太阳紫外线诱导的皮肤炎症。
生物活性

Cephradine (Cefradine) monohydrate is a broad-spectrum and orally active cephalosporin. Cephradine monohydrate is active against both grampositive and gram-negative pathogens and effective in eradicating most penicillinase-producing organisms known to be resistant to penicillin G, penicillin V, and ampicillin. Cephradine monohydrate has been used in the research of genitourinary, gastrointestinal and respiratory tract infections, and in infections of the skin and soft tissues. Cephradine monohydrate blocks solar-ultraviolet induced skin inflammation through direct inhibition ofTOPK[1][2][3].

IC50& Target

β-lactam

 

体外研究
(In Vitro)

Cephradine (0~8 μg/mL; 12 hours) makes bacterial viability rapidly increased at antibiotic concentrations below the MIC (minimum inhibitory concentration) of 0.70 μg/mL at both pH 7.4 and pH 5.5[4].

体内研究
(In Vivo)

Cephradine (25 mg/kg; s.c.; 11 days) reduces the bacterial density and counts in the abscesses[4].

Animal Model:Nondiabetic mice
Dosage:25 mg/kg
Administration:S.c.; 11 days
Result:Reduced the bacterial density and counts in the abscesses.
Clinical Trial
分子量

367.42

Formula

C16H21N3O5S

CAS 号

75975-70-1

中文名称

头孢拉定一水合物; 头孢环己烯一水合物; 头孢拉啶一水合物

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.