Aurora/LIM kinase-IN-1 (Compound F114) is a potent and dual inhibitor ofauroraandlimkinase. Aurora kinases and lim kinases are involved in neoplastic cell division and cell motility, respectively. Aurora/LIM kinase-IN-1 inhibits GBM proliferation and invasion. Aurora/LIM kinase-IN-1 is a promising new scaffold for dual aurora/lim kinase inhibitors that may be used in future drug development efforts for GBM, and potentially other cancers^[1].

312.37

C₁₆H₂₀N₆O

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