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Graphislactone A
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Graphislactone A图片
CAS NO:52179-44-9
包装与价格：
包装价格(元)
1mg电议
5mg电议

产品介绍
Cas No.52179-44-9
化学名4,7-dihydroxy-3,9-dimethoxy-1-methyl-6H-dibenzo[b,d]pyran-6-one
Canonical SMILESO=C1OC2=C(O)C(OC)=CC(C)=C2C3=C1C(O)=CC(OC)=C3
分子式C16H14O6
分子量302.3
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Graphislactone A is an antioxidant produced by Cephalosporium IFB-E001 and M. olivacea. It exhibits dose-dependent scavenging activity against DPPH radicals and metal ion-dependent hydroxyl radicals in vitro. Graphislactone A reduces peroxidation of human LDL and slows peroxidation of linoleic acid by 4.4-fold. It also inhibits acetylcholinesterase (AChE) with an IC50 value of 27 μM.

References:
[1]. Song, Y.C., Huang, W.Y., Sun, C., et al. Characterization of graphislactone A as the antioxidant and free radical-scavenging substance from the culture of Cephalosporium sp. IFB-E001, an endophytic fungus in Trachelospermum jasminoides Biol. Pharm. Bull. 28(3), 506-509 (2005).
[2]. Hormazabal, E., Schmeda-Hirschmann, G., Astudillo, L., et al. Metabolites from Microsphaeropsis olivacea, an endophytic fungus of Pilgerodendron uviferum Z. Naturforsch. C. 60(1-2), 11-21 (2005).