Cetrorelix Acetate (SB-75 acetate) is a potent gonadotropin-releasing hormone(GnRH)receptor antagonist with anIC₅₀of 1.21 nM^[1].

IC50: 1.21 nM GnRH^[1].

Cetrorelix Acetate inhibits growth of ES-2 cell line at 1000 ng/ml. Cetrorelix Acetate has comparable antiproliferative effects as GnRH-I agonists indicating that the dichotomy of GnRH-I agonists and antagonists might not apply to the GnRH-I system in cancer cells^[2].

1491.09

Solid

C₇₂H₉₆ClN₁₇O₁₆

145672-81-7

N-acetyl-{2-Naph-Ala}-{Cl-Phe}-{3Py-Ala}-Ser-Tyr-{Cit}-Leu-Arg-Pro-Ala-NH2

Ac-{2-Naph-Ala}-{Cl-Phe}-{3Py-Ala}-SY-{Cit}-LRPA-NH2

醋酸西曲瑞克

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

DMSO : 50 mg/mL(33.53 mM;Need ultrasonic)

H₂O : 2 mg/mL(1.34 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture and light)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。