Intepirdine HCl (GSK-742457; SB742457; RVT-101), the hydrochloride salt of Intepirdine, is a novel, potent and highly selective 5-HT6 receptor antagonist with pKi of 9.63; it exhibits >100-fold selectivity over other receptors. Intepirdine has potential cognition, memory, and learning-enhancing effects. It was being studied by GlaxoSmithKline for the treatment of Alzheimer's disease and demonstrated some preliminary efficacy in phase II clinical trials. SB742457 can reverse age-related declines in delayed non-match-to-sample performance (DNMS). SB742457 shows increasing pro-cognitive effects in patients with AD.

纯度：≥98%