Phycocyanobilin

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Phycocyanobilin

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

20298-86-6

包装与价格：

包装	价格(元)
5mg	电议
10mg	电议
25mg	电议

产品名称

藻青素；藻蓝素

产品介绍

Phycocyanobilin 是一种具有口服活性的抗氧化剂 (reactive oxygen species)，是一种有效的活性氧清除剂。Phycocyanobilin 可用于阿尔茨海默病的研究。

生物活性

Phycocyanobilin, an orally active antioxidative agent, is an effective scavenger for variousreactive oxygen species. Phycocyanobilin can be used for the research of Alzheimer’s disease^[1]^[2]^[3].

体外研究
(In Vitro)

Phycocyanobilin (100 μM; 0-250 min) 抑制亚油酸甲酯的过氧化，并产生较长的诱导期^[1]。
Phycocyanobilin (1 mM; 0-300 min) 抑制脂质体的氧化^[1]。

体内研究
(In Vivo)

Phycocyanobilin (15 mg/kg; p.o.; in diet for 2 weeks) 在 2 型糖尿病小鼠中显示抗氧化作用^[3]。

Animal Model:	Male C57BL/Ks Jdb/dbmice, a rodent model for type 2 diabetes^[3]
Dosage:	15 mg/kg
Administration:	In diet for 2 weeks
Result:	Significantly decreased blood glucose levels. Normalized the increases in urinary 8-OHdG and 8-epi-PGF_2αlevels, renal oxidative stress markers evaluated by renal 8-OHdG staining and DHE staining, Nox4 mRNA, and protein expression, as well as the mRNA levels of other NAD(P)H oxidase components, inflammatory markers and HO-1.

分子量

586.68

性状

Solid

Formula

C₃₃H₃₈N₄O₆

CAS 号

20298-86-6

中文名称

藻青素；藻蓝素

结构分类

Ketones, Aldehydes, Acids

来源

Spirulina platensis

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据

In Vitro:

DMSO :< 1 mg/mL (ultrasonic;heat to 60℃)(insoluble or slightly soluble)