α-MSH (α-Melanocyte-Stimulating Hormone), an endogenous neuropeptide, is an endogenousmelanocortin receptor4 (MC4R)agonist with anti-inflammatory and antipyretic activities. α-MSH is a post-translational derivative of pro-opiomelanocortin (POMC)^[1][2].

MC4R^[2]

α-MSH modulates CNS inflammation by acting directly on melanocortin receptors in glial cells. α-MSH modulates NFκB activation. α-MSH inhibits translocation of transcription factor κB to the nucleus^[3].

α-MSH (50 μg/0.2 ml saline; i.p.) given systemically effectively modulates inflammatory reactions^[3].

1664.88

Solid

C₇₇H₁₀₉N₂₁O₁₉S

581-05-5

Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2

Ac-SYSMEHFRWGKPV-NH2

α-黑素细胞刺激激素 (MSH)，酰胺

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

H₂O : 25 mg/mL(15.02 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。