Digitonin, a glycoside obtained from Digitalis purpurea, could increase cell permeability by binding tocholesterolmolecules and reduce tumor growth^[1]. Digitonin is an natural detergent^[2].

Digitonin, a detergent that increases cell permeability by binding to cholesterol molecules in the cell membrane, can increase cisplatin accumulation and reduce tumour growth in vitro^[1].

In the liver parenchyma the concentrations are of the same magnitude. Measured with the¹³³Xe-clearance technique, Digitonin does not alter the tumor blood flow. Digitonin enhances the tumor-growth retarding effect of CBDCA given intra-aterially at 5 mg/kg but not at 25 mg/kg^[1].

1229.31

Solid

C₅₆H₉₂O₂₉

11024-24-1

洋地黄皂苷；毛地黄皂苷

• Steroids

• Plants
• Scrophulariaceae
• Digitalis purpureaLinn.

Room temperature in continental US; may vary elsewhere.

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

H₂O : 100 mg/mL(81.35 mM;Need ultrasonic)

DMSO : 100 mg/mL(81.35 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (stored under nitrogen)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用； 以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

• 1.

  请依序添加每种溶剂： PBS

  Solubility: ≥ 25 mg/mL (20.34 mM); Clear solution