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SYM 2081
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SYM 2081图片
CAS NO:31137-74-3
包装与价格:
包装价格(元)
10mg电议
50mg电议

产品介绍
SYM 2081 是一种高亲和力配体和有效的红藻氨酸受体激动剂,抑制 [3H]-红藻氨酸结合,IC50 为 35 nM,对红藻氨酸受体的选择性分别是 AMPA 和 NMDA 受体的近 3000 倍和 200 倍[1 ]。
Cas No.31137-74-3
别名(2S,4R)-4-甲基谷氨酸
化学名(2S,4R)-2-amino-4-methylpentanedioic acid
Canonical SMILESC[C@](C(O)=O)([H])C[C@@](N)([H])C(O)=O
分子式C6H11NO4
分子量161.16
溶解度<8.06mg/ml in Water
储存条件Store at RT
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

SYM 2081 is a high-affinity ligand and potent, selective agonist of kainate receptors, inhibits [3H]-kainate binding with an IC50 of 35 nM, almost 3000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively[1].

References:
[1]. Lee JY, et al. Furthering pharmacological and physiological assessment of the glutamatergic receptors at the Drosophila neuromuscular junction. Comp Biochem Physiol C Toxicol Pharmacol. 2009 Nov;150(4):546-57.