PPNDS 是一种选择性和竞争性的 meprin ⋲；抑制剂 (IC50: 80 nM, Ki: 8 nM)，并且还抑制 ADAM10 (IC50: 1.2 μM)。
| Cas No. | 1021868-77-8 |
| 化学名 | sodium (Z)-3-(2-(4-formyl-6-methyl-5-oxo-3-((phosphonatooxy)methyl)pyridin-2(5H)-ylidene)hydrazinyl)-7-nitronaphthalene-1,5-disulfonate |
| Canonical SMILES | [O-]S(=O)(C1=CC(N/N=C(C(COP([O-])([O-])=O)=C2C=O)\N=C(C)C2=O)=CC(C1=CC([N+]([O-])=O)=C3)=C3S([O-])(=O)=O)=O.[Na+].[Na+].[Na+].[Na+] |
| 分子式 | C18H11N4Na4O14PS2 |
| 分子量 | 694.36 |
| 溶解度 | Soluble to 100 mM in Water |
| 储存条件 | Desiccate at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
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