Fluoroclebopride 可逆地与多巴胺受体结合。
| Cas No. | 154540-49-5 |
| 别名 | 4-氨基-5-氯-N-[1-[(4-氟苯基)甲基]-4-哌啶基]-2-甲氧基苯甲酰胺 |
| Canonical SMILES | COC1=C(C(NC2CCN(CC3=CC=C(F)C=C3)CC2)=O)C=C(Cl)C(N)=C1 |
| 分子式 | C20H23ClFN3O2 |
| 分子量 | 391.9 |
| 溶解度 | DMF: 20 mg/ml,DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Fluoroclebopride is a benzamide analog that is used in positron emission tomography (PET) applications. It binds reversibly to dopamine receptors (Kis = 0.95, 5.7, 5.46, and 144 nM for D2-like, D2(long), D3, and D4 receptors, respectively, in radioligand binding assays). It is selective for these receptors over D1, serotonin 5-HT2, and α2-adrenergic receptors (Kis = >10,000, 283, and 1,300 nM, respectively). A fluorine-18 moiety has been used to label this compound for use as a probe for studying D2/D3 receptor availability via PET in various monkey models. |
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