包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
生物活性 | S961 acetate is an high-affinity and selectiveinsulin receptor(IR) antagonist withIC50s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and humaninsulin-like growth factor Ireceptor (HIGF-IR) in SPA-assay, respectively[1]. | ||||||||||||||||
体外研究 (In Vitro) | S961 also shows high-affinity to Rat IR and Pig IR with IC50s of 0.056 nM and 0.084 nM in PEG-assay, respectively[1]. | ||||||||||||||||
分子量 | 4864.18 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C213H301N55O72S2 | ||||||||||||||||
Sequence | Gly-Ser-Leu-Asp-Glu-Ser-Phe-Tyr-Asp-Trp-Phe-Glu-Arg-Gln-Leu-Gly-Gly-Gly-Ser-Gly-Gly-Ser-Ser-Leu-Glu-Glu-Glu-Trp-Ala-Gln-Ile-Gln-Cys-Glu-Val-Trp-Gly-Arg-Gly-Cys-Pro-Ser-Tyr (Disulfide bridge: Cys33-Cys40) | ||||||||||||||||
Sequence Shortening | GSLDESFYDWFERQLGGGSGGSSLEEEWAQIQCEVWGRGCPSY (Disulfide bridge: Cys33-Cys40) | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) | ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 12.5 mg/mL(2.57 mM;Need ultrasonic) H2O : 1.79 mg/mL(0.37 mM;ultrasonic and adjust pH to 8 with NaOH) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |