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N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid图片
CAS NO:24967-27-9
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
N-acetyl-2,3-dehydro-2-Deoxyneuraminic Acid (Neu5Ac2en) 是一种有效的神经氨酸酶（唾液酸酶）抑制剂。
Cas No.24967-27-9
别名N-乙酰-2,3-二脱氢-2-脱氧神经氨酸,Neu5Ac2en; DANA
Canonical SMILESOC(C1=C[C@H](O)[C@@H](NC(C)=O)[C@@]([C@H](O)[C@H](O)CO)([H])O1)=O
分子式C11H17NO8
分子量291.3
溶解度DMF: 0.1 mg/ml,DMSO: 1 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

N-acetyl-2,3-dehydro-2-Deoxyneuraminic acid (DANA) is an inhibitor of human neuriminidases (sialidases) NEU1-4 (IC50s = 143, 43, 61, and 74 μM, respectively). In vivo, DANA (30 μL of a 5 mM solution) reduces latency to first seizure and increases seizure duration in a rat model of potassium-induced seizures.