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NG 012
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NG 012图片
CAS NO:141731-76-2
包装与价格:
包装价格(元)
500μg电议
1mg电议
5mg电议

产品介绍
NG 012,神经生长因子 (NGF) 增强剂,是从疣状青霉 F-4542 的培养液中分离得到的。 NG 012 可增强 NGF 在大鼠嗜铬细胞瘤细胞系 (PC12) 中诱导的神经突生长。
Cas No.141731-76-2
Canonical SMILESOC(C=C1O)=CC(C[C@@H](C)OC(C[C@@H](C)OC(C2=C(O)C=C(O)C=C2C[C@@H](C)OC(C[C@@H](CO)OC(C[C@@H](C)O3)=O)=O)=O)=O)=C1C3=O
分子式C32H38O15
分子量662.6
溶解度Chloroform: Soluble,Ethanol: Soluble,Methanol: Soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

NG 012 is a fungal metabolite originally isolated from P. verruculosum that has fungicidal and nerve growth factor-potentiating properties. It inhibits the growth of the plant pathogenic fungi B. cinerea, P. teres, P. lingam, S. sclerotiorum, and M. fructigena in vitro. NG 012 (50 μM) increases the efficacy of the antifungal miconazole against C. albicans, reducing the IC50 value from 19.2 to 2.5 μM. It also potentiates neurite outgrowth induced by nerve growth factor (NGF) in PC12 cells in a concentration-dependent manner.