NIAD-4 is a fluorescent probe that crosses the blood-brain barrier to bind with high affinity to amyloid-β (Aβ) plaques (Ki = 10 nM).
Cas No. | 868592-56-7 |
Canonical SMILES | OC1=CC=C(C2=CC=C(C3=CC=C(/C=C(C#N)/C#N)S3)S2)C=C1 |
分子式 | C18H10N2OS2 |
分子量 | 334.4 |
溶解度 | DMF: 25 mg/mL,DMSO: 25 mg/mL,DMSO:PBS(pH 7.2) (1:2): 0.3 mg/mL,Ethanol: 0.2 mg/mL |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | NIAD-4 is a fluorescent probe that crosses the blood-brain barrier to bind with high affinity to amyloid-β (Aβ) plaques (Ki = 10 nM). It displays excitation/emission spectra of 475/625 nm, respectively, with the far-red emission occurring upon binding to Aβ. |