MI 14 is a selectivePI4KIIIβinhibitor withIC₅₀s of 54 nM, >100 μM, >100 μM forPI4KIIIβ,PI4KIIIα, PI4KIIα, respectively. MI 14 has antiviral activity againstHCV1b, CVB3, HRVM, HVC 2a^[1].

MI 14 (化合物 36t) 对 HeLa 细胞中的 HCV 1b (EC₅₀=0.087 μM)、CVB3 (EC₅₀=0.145 μM)、HRVM (EC₅₀=1.03 μM)、HVC 2a (EC₅₀=10.6 μM) 具有抗病毒活性^[1]。
MI 14 对磷脂酰肌醇 3 激酶 (PI3Ka、PI3Kb、PI3Kd 和 PI3Kg) 没有抑制作用，IC₅₀高达 10 μM^[1]。

450.94

C₁₉H₂₃ClN₆O₃S

1715934-43-2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.