头孢替坦（钠盐）是一种半合成头霉素抗生素，通过抑制细胞壁合成发挥杀菌作用。
| Cas No. | 74356-00-6 |
| 别名 | 头孢替坦二钠 |
| Canonical SMILES | O=C(N[C@@]1(OC)[C@](SCC(CSC2=NN=NN2C)=C3C([O-])=O)([H])N3C1=O)C4S/C(S4)=C(C([O-])=O)\C(N)=O.[Na+].[Na+] |
| 分子式 | C17H15N7O8S4•2Na |
| 分子量 | 619.6 |
| 溶解度 | DMF: 3 mg/ml,DMSO: 10 mg/ml,PBS (pH 7.2): 10 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Cefotetan is a cephamycin antibiotic that is active against both Gram-positive and Gram-negative bacteria including isolates of E. coli, S. aureus, K. pneumoniae, and P. maltophilia (MICs = 0.03-32 mg/ml). It reduces mortality by 50% in a rabbit model of fecal peritonitis when administered at a dose of 25 mg/kg twice daily. Formulations containing cefotetan have been used in the treatment of various bacterial infections. |
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