CAS NO: | 29400-42-8 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
Cas No. | 29400-42-8 |
别名 | 煙麴黴酸,Fumigacin |
Canonical SMILES | CC(O[C@H]1C[C@]2(C)[C@@]3(C)C([C@@H](OC(C)=O)[C@@]4([H])[C@H](C)C(C=C[C@]4(C)[C@]3([H])CC[C@@]2([H])/C1=C(C(O)=O)\CC/C=C(C)/C)=O)=O)=O |
分子式 | C33H44O8 |
分子量 | 568.7 |
溶解度 | DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Helvolic acid is a mycotoxin originally isolated from A. fumigatus that has broad-spectrum antibiotic activity against Gram-positive and Gram-negative bacteria. At 4-16 mg/L, it acted synergistically with erythromycin (500-2,000 mg/L) in vitro on five multi-drug resistant strains of S. aureus. At 10 mg/kg/d, it reduced tumor growth and prolonged survival synergistically with cyclophosphamide (20 mg/kg/d) in a mouse model of sarcoma but had no effect when administered alone. |