Integracin B 是一种有效的 HIV-1 整合酶二聚体烷基芳香族抑制剂,通过体外试验筛选真菌提取物而发现。
Cas No. | 224186-05-4 |
Canonical SMILES | OC1=CC(O)=C(C(O[C@H](CCC)CCCCCCCC2=CC(O)=CC(O)=C2)=O)C(CCCCCCC[C@@H](CCC)O)=C1 |
分子式 | C35H54O7 |
分子量 | 586.8 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Integracin B is a fungal metabolite and an inhibitor of HIV-1 integrase (IC50 = 6.1 μM in an HIV-1 integrase coupled assay). It also inhibits HIV-1 integrase in a strand transfer assay (IC50 = 17 μM). |