CAS NO: | 329-98-6 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
100mg | 电议 |
500mg | 电议 |
1 g | 电议 |
5 g | 电议 |
生物活性 | PMSF is an irreversibleserine/cysteine proteaseinhibitor commonly used in the preparation of cell lysates. | ||||||||||||||||
体外研究 (In Vitro) | PMSF (2 mM) inhibits carbachol-stimulated inositol phosphate accumulation in the presence of Li+by only 15%-19%. PMSF inhibition of phosphoinositide turnover is due to one or more steps following phosphoinositide breakdown[1]. PMSF inhibits the acylation of the inositol residue of GPI intermediates in bloodstream formT. brucei. PMSF inhihits the formntion of glycolipid C but does not inhibit fatty acid remodeling in vitro. PMSF inhihits GPI acylation and ethanolamine phosphatp addition in procyclic trypanosomes but not in Hela cells[2]. | ||||||||||||||||
体内研究 (In Vivo) | PMSF (0.1 mL/10 g b.wt, i.p.) produces antinociception as indicated by the dose-responsive increase in % MPE in the tail-flick latency evaluation, but fails to produce a clear dose-responsive inhibition of locomotion. Mice receiving i.p. injections of PMSF exhibit cannabinoid effects that includes antinociception, hypothermia and immobility with ED50values of 86, 224 and 206 mg/kg, respectively. PMSF (30 mg/kg) pretreatment potentiates the effects of anandamide on tail-flick response (antinociception), spontaneous activity and mobility by 5-, 10- and 8-fold, respectively[3]. | ||||||||||||||||
分子量 | 174.19 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C7H7FO2S | ||||||||||||||||
CAS 号 | 329-98-6 | ||||||||||||||||
中文名称 | 苯甲基磺酰氟;苄磺酰氟;苄基磺酰氟;苯甲磺酰氟;苯磺基氟化物;苯甲基磺酰氟化物;苯甲基磺酰化氟 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
| ||||||||||||||||
溶解性数据 | In Vitro: DMSO : 250 mg/mL(1435.21 mM;Need ultrasonic) Isopropanol : 60 mg/mL(344.45 mM;Need ultrasonic) H2O :< 0.1 mg/mL(insoluble) 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
|