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Pioglitazone Ketone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pioglitazone Ketone图片
CAS NO:146062-45-5
包装:5mg
市场价:9752元

产品介绍
Pioglitazone ketone is an active metabolite of the PPARγ agonist pioglitazone.
Cas No.146062-45-5
别名吡格列酮
Canonical SMILESCC(C1=CN=C(CCOC2=CC=C(CC3SC(NC3=O)=O)C=C2)C=C1)=O
分子式C19H18N2O4S
分子量370.4
溶解度Chloroform: soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Pioglitazone ketone is an active metabolite of the PPARγ agonist pioglitazone . Formation of pioglitazone ketone occurs primarly through cytochrome P450 (CYP) isoform CYP2C8-mediated metabolism of pioglitazone. Pioglitazone ketone (100 mg/kg in the diet) reduces blood glucose levels in a KKAy mouse model of type 2 diabetes.