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Carbazeran
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Carbazeran图片
CAS NO:70724-25-3
包装与价格:
包装价格(元)
500μg电议
1mg电议
5mg电议
10mg电议

产品介绍
Carbazeran 是一种有效的磷酸二酯酶抑制剂,是醛氧化酶的底物。
Cas No.70724-25-3
别名卡巴折伦
Canonical SMILESCOC1=C(OC)C=C(C=NN=C2N3CCC(OC(NCC)=O)CC3)C2=C1
分子式C18H24N4O4
分子量360.4
溶解度Chloroform: Slightly Soluble,Methanol: Slightly Soluble
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Carbazeran is an inhibitor of phosphodiesterase 2 (PDE2) and PDE3. It inhibits cAMP hydrolysis (IC50 = 4.1 µM in rabbit heart ventricles) selectively over cGMP hydrolysis (IC50 = 171 µM). It induces positive inotropic (EC50 = 100 µM) and negative chronotropic effects in isolated rabbit papillary muscle and right atria, respectively. Carbazeran is also a substrate for the enzyme aldehyde oxidase (AOX1), which is involved in the metabolism of xenobiotics.